Comprehensive, up-to-date, evidence-based COVID19 drug-drug interaction resource, freely available to healthcare workers, patients and researchers.

The Programme Steering Committee (PSC) provides independent expert oversight of the Liverpool Drug Interactions programme, including the web- and app-based prescribing tools …

In order to address this, the Liverpool Drug Interactions website team developed this freely available drug interactions resource to provide information on the likelihood of interactions …

Coadministration is contraindicated as it may lead to a loss of virological response and possible resistance. Coadministration of carbamazepine (300 mg twice daily for 16 doses) and …

These resources are freely available and the Liverpool Drug Interactions Group would like to encourage the dissemination (with an appropriate acknowledgement) of this drug-drug …

Coadministration has not been studied. Apixaban is a substrate of P-gp and is metabolized by CYP3A4. Concentrations of apixaban are expected to increase due to CYP3A4 and P-gp …

Nov 27, 2023 · A further seventeen new comedications have been added to the interaction checker: Antibacterials: Fosfomycin Anti-diabetics: Alogliptin Antifungals: Clotrimazole ...

Coadministration has not been studied. Ezetimibe is glucuronidated by UGTs 1A1 and 1A3 and to a lesser extent by UGTs 2B15 and 2B7. Ezetimibe is a substrate of OATP1B1.

Coadministration with nirmatrelvir/ritonavir has not been studied. Colchicine is a CYP3A4 and P-gp substrate. Coadministration of ritonavir (100 mg twice daily for 5 days) and colchicine (0.6 …

Coadministration of remdesivir and chloroquine phosphate or hydroxychloroquine sulphate is not recommended based on in vitro data demonstrating an antagonistic effect of chloroquine on …