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This project aims to develop techniques that will allow scientists to build ever larger lengths of DNA from scratch in the laboratory, with the goal of understanding better how our genomes work, and ...
CAR-T is a powerful tool which is still evolving. Here we highlight what is new in CAR-T cell therapy Cancer cells often play hide-and-seek with the immune system in an attempt to evade catastrophic ...
Why is ctDNA testing important? Traditional tissue biopsies for diagnosis can be difficult to perform and present risks to patients, particularly those who are very unwell. Up to 30,000 patients per ...
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A new type of medicine that uses an approach called ‘gene silencing’ has been approved for use in the National Health Service (NHS) in England. The medicine, patisiran (brand name Onpattro) is used ...
By tailoring drug treatments to individuals based on their genetic makeup, pharmacogenomics has been promising to transform drug prescribing for some years. Recent advancements and the increasing use ...
With the recent launch of its infectious diseases strategy, Public Health England (PHE) has outlined is ambitions for the next five years in terms of its core mission “to prevent, detect, respond to ...
The European Health Data Space Regulation has arrived but will its mandatory sharing requirement be its tour de force or Achilles’ heel? The Regulation amounts to an ambitious and laudable step ...
Antimicrobial resistance (AMR) is one of the greatest challenges facing health systems, causing an estimated 4.71 million deaths globally in 2021. It has been ten years since the World Health ...
Integration of polygenic scores (PGS) into clinical practice requires robust, validated mechanisms to generate these scores. A consistent message in our reports has been that to deliver PGS-based ...
The rapid development, approval and roll out of multiple vaccines against SARS-CoV-2, the virus that causes COVID-19, is an impressive achievement for science and healthcare. The virus genome was ...
Each year, zettabytes of data are produced globally, which is comparable to the number of stars in the observable universe. This number is increasing at a rapid pace, and in 2025, global yearly data ...
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