In a June 12 conference at UW-Madison, researchers gathered from across the U.S. and abroad to discuss the latest progress on TDP-43 biomarkers. In all, 74 people attended in person, and 727 virtually ...

Anatomy explorers have charted a new path myeloid cells use to access the brain. On 3 June in Neuron, scientists led by Lindsay Hohsfield and Kim Green, both at the University of California, Irvine, ...

Massage might help your brain flow regain its mojo. On June 4 in Nature, researchers led by Gou Young Koh at the Institute for Basic Science in Daejeon, South Korea, mapped the labyrinth of lymphatics ...

For years, scientists have been working toward blood tests for Alzheimer’s disease that could be used routinely in clinical practice. Now, they are on the cusp. At this year’s ADPD conference, held ...

Over the last 40 years, age-adjusted dementia prevalence in the U.S. has dropped by two-thirds. This predicts a 25 percent rise in total dementia cases by 2050, due to population aging. The findings ...

This article discusses the role of receptors and lysosomal dysfunction in APOE variant-related Alzheimer's disease risk.

“It was surprising to see C1q have such a profound effect on neuronal function,” Scott-Hewitt told Alzforum. She believes C1q may regulate translation in neurons of younger mice, but with age, these ...

Series - AD/PD™ 2024: Advances in Science & Therapy: Part 1 of 9: Fast Plaque Clearance with Little ARIA? So Teases Trontinemab at AD/PD 2024 Part 2 of 9: TauRx Parses Subgroups to Make the Case for ...

Several people who received Aβ-contaminated growth hormone in childhood developed dementia in midlife. Four of them had biomarker or pathological evidence of Alzheimer’s disease. This is the first ...

Studies aim to validate Alzheimer's disease blood tests against gold standard biomarkers in primary care. Scientists ask how best to incorporate AD blood tests into existing healthcare systems. Some ...

Scientists reported results of a round-robin comparison of more than two dozen plasma phospho-tau assays. (Hint: p-tau 217 tests outdid the rest of the flock.) A clearer picture emerged of how plasma ...