which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the process of transcription is the complex of ...
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...
More information: Yuki Aoi et al, SPT5 regulates RNA polymerase II stability via Cullin 3–ARMC5 recognition, Science Advances (2025). DOI: 10.1126/sciadv.adt5885 Provided by Northwestern University ...
Transcription initiation begins with the binding of RNA polymerase, a multi-subunit enzyme, to a specific DNA sequence called the promoter region. Prokaryotic promoters typically contain a Pribnow ...