ascopubs.org

Comparison of tissue based FGFR mutation detection by Therascreen FGFR with UroTyper FGFR and ADC test and relevance for potential co-targeting with TROP2 and NECTIN4: Preview ...

Effect of neutrophil to lymphocyte ratio (NLR) on outcomes with immune checkpoint inhibitors (ICIs) in patients (pts) with metastatic urothelial carcinoma (mUC) in real-world setting. This is an ASCO ...
The American Journal of Managed Care

Study: FGFR mRNA Overexpression Occurs Frequently for Those With Cholangiocarcinoma

Investigators also confirmed that FGFR2 fusion–positive tumors have a higher expression of FGFR2 but were not associated with higher expression of FGFR1, FGFR3, or FGFR4. Investigators concluded that ...
EurekAlert!

AACR: Early trial results show benefits of FGFR inhibitors and PARP/ATR inhibitor combinations in multiple tumor types

The FIGHT-207 trial, led by Jordi Rodon, M.D., Ph.D., associate professor of Investigational Cancer Therapeutics, demonstrated promising early signs of clinical benefit and unveiled potential ...
ascopubs.org

Functional Characterization of Variants of Unknown Significance of Fibroblast Growth Factor Receptors 1-4 and Comparison With AI Model–Based Prediction

Molecular Correlates of Long-Term Response to Bevacizumab in Glioblastoma Recurrent nonkinase domain FGFR VUS variants were collected from the Catalog of Somatic Mutations in Cancer and their ...
EurekAlert!

Unlocking bone repair: FGFR antagonists restore mandibular bone repair in osteochondrodysplasia

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...