JCO PO author Dr. Jun Gong shares insights into his JCO PO articles, “Phase II Study of Erdafitinib in Patients with Tumors with FGFR Amplifications: Results from the NCI-MATCH ECOG-ACRIN Trial ...

To expand the scope and prolong the strategy of FGFR inhibition, understanding mechanisms of primary and acquired resistance is crucial. While little is known about clinical resistance to erdafitinib, ...

Aberrations in fibroblast growth factor receptors FGFR2/3 are major drivers of many cancers-including intrahepatic ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

The Ohio State University researchers are also hoping to enroll patients for a trial that is specific to pancreatic cancer patients with the FGFR gene mutation. Make wishtv.com your home page ...

About 5% of cancers involve a mutation of the gene that controls proteins called fibroblast growth factor receptors (FGFR). This mutation causes cancers to grow rapidly and spread.

FGFR mutation or overamplification has been shown to cause breast, lung, endometrial, and gastric cancers, as well as hepatocellular carcinoma. There are currently 3 FDA-approved FGFR inhibitors ...

That’s when Bob’s doctor referred him to Doctor Sameek Roychowdhury, who determined that Bob had a rare FGFR mutation fueling his cancer. Dr.

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...