EMBO Press2d
Mouse promoters are characterised by low occupancy and high turnover of RNA polymerase II
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
Frontiers29d
Genetic Regulation of N6-Methyladenosine-RNA in Mammalian Gametogenesis and Embryonic Development
TABLE 1. Functional roles of m 6 A regulators in RNA metabolism. It has been confirmed that for most cells in reproductive and other systems, the precise regulation of gene expression occurs at the ...
Frontiers1mon
Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase
PrimPols are a class of primases that belong to the archaeo-eukaryotic primase (AEP) superfamily but have both primase and DNA polymerase activities. Replicative polymerase from NrS-1 phage (NrSPol) ...
eLife5y
Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
To ensure that RNA polymerase II copies the correct genes at the correct ... Collectively these PTMs and recruited protein factors constitute the ‘CTD Code’ for eukaryotic transcription (Buratowski, ...
eLife12y
Mechanism for priming DNA synthesis by yeast DNA Polymerase α
The DNA Polymerase α (Pol α)/primase complex initiates DNA synthesis in eukaryotic replication. In the complex, Pol α and primase cooperate in the production of RNA-DNA oligonucleotides that prime ...