The dwarf planet, which is roughly the size of Pluto, takes about 285 years to orbit the sun, and its distance from Earth varies from 34 to 51 astronomical units, or AU (one AU is the distance ...

More information: FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development, Cancer Research (2025). DOI: 10.1158/0008-5472.CAN-24-4576 ...

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2 ...

In February 2025, Insilico published a research paper in the Journal of Medicinal Chemistry entitled "Discovery of Pyrrolopyrazine Carboxamide Derivatives as Potent and Selective FGFR2/3 ...

When they targeted FGFR2 along with EGFR-a protein known to be overactive in pancreatic cancer-they saw even better results. Fewer "early versions of cancer" formed in the first place.

“These data provide important early evidence that RLY-4008, or lirafugratinib, has the potential to help both patients with FGFR2-fusion cholangiocarcinoma as previously reported, as well as ...

Aberrations in fibroblast growth factor receptors FGFR2/3 are major drivers of many cancers—including intrahepatic cholangiocarcinoma, endometrial, breast, gastric, and bladder cancers. However ...