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Neoadjuvant therapies ready to cure?

Neoadjuvant therapy plays an increasingly important role in the multidisciplinary management of gastrointestinal cancers.
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Mycosis fungoides with Sézary syndrome mimicking erythrodermic drug eruption

Primary cutaneous T‑cell lymphomas (CTCLs) represent a heterogenous group of lymphomas that manifest within the skin, without any extracutaneous involvement at the initial diagnosis [ 1 ]. This ...
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Primary central nervous system tumors: future directions in systemic treatment

Primary central nervous system (CNS) tumors pose significant challenges due to their heterogeneous nature, frequently limited prognosis, and substantial impact on quality of life. Despite advances in ...
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Targeted therapies in advanced cholangiocarcinoma: new targets and strategies

Ein fortgeschrittenes Cholangiokarzinom ist trotz platinbasierter Standardchemotherapie mit einer schlechten Prognose ...
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Cerebral vasculitis as a severe complication of acute infectious meningoencephalitis—a case series of five different pathogens

Infectious meningoencephalitis, characterized by inflammation of both the brain and adjacent meninges, is caused by a variety ...
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Relevance of balneotherapy for back pain—a systematic literature review covering the past 5 years

Balneotherapy is defined as the use of natural healing waters (including gases, aerosols, etc.), whereby healing waters are ...
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Turning the lens on women in surgery

Dr. Sarah Temkin ist Regisseurin und Produzentin von 1001 Cuts. Als gynäkologische Onkologin mit über zwanzig Jahren ...
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ASCO 2025 highlights: emerging therapies and biomarkers in pancreatic ductal adenocarcinoma

At ASCO 2025, several promising studies in pancreatic ductal adenocarcinoma (PDAC) were presented. In the neoadjuvant setting, the CASSANDRA trial compared the PAXG (nab-paclitaxel, capecitabine, ...
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Gewalt sehen, Spuren sichern, Betroffene stärken: Warum Wien eine eigene Untersuchungsstelle braucht

In der neuen Untersuchungsstelle für Gewaltbetroffene an der MedUni Wien widmet sich die Gerichtsmedizinerin Dr. Katharina ...
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Neoadjuvant therapy

Neoadjuvant therapy (NAT) for early breast cancer was first introduced in the 1980s to downstage large, inoperable tumors, and thereby enable less extensive surgical resections. Beyond its surgical ...
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Die Lebensgeschichte der Arterie

Die Aorta erzählt ihre eigene Geschichte – von kindlicher Reinheit über die ersten molekularen Irritationen bis hin zum kalzifizierten Stillstand.
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Current smoking is an independent risk factor for 30-day mortality and morbidities after esophagectomy: an analysis of the American College of Surgeons National Surgical ...

While converging evidence suggests that current smoking does not affect long-term survival after esophagectomy, the impact of current smoking on short-term outcomes remains inconclusive based on ...