2 Minute Medicine

Visual perturbation training may be superior to treadmill training for reduction of fall risk in Parkinson’s disease

Six weeks of visual perturbation training reduced visual dependency and improved temporal gait characteristics to a greater extent than treadmill training alone in people with early-stage Parkinson’s ...
2 Minute Medicine

Shingles vaccine and sildenafil linked to lower Alzheimer’s risk

An expert panel identified the shingles vaccine and sildenafil as the top candidates for repurposing to protect against Alzheimer's disease. 2. Leveraging existing drugs with established safety data ...
2 Minute Medicine

Glucagon-like peptide-1 receptor agonists are associated with reduced risk of developing substance use disorders

Use of glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced risk of developing substance use disorders among US veterans with type 2 diabetes. Evidence Rating Level: 2 (Good) ...
2 Minute Medicine

Oral infigratinib boosts growth velocity in achondroplasia study

Oral infigratinib achieved the highest growth velocity reported to date in a randomized achondroplasia trial, growing 2.10 cm ...
2 Minute Medicine

Computed tomography angiography of the head and neck may inform emergency management in patients with suspected stroke

Computed tomography angiography of the head and neck (CTAHN) is most likely to reveal an acute finding that changes emergency management in patients presenting with suspected stroke, especially when ...
2 Minute Medicine

The quadrivalent human papillomavirus vaccine provides effective and durable protection against invasive cervical cancer

In this cohort study, the quadrivalent human papillomavirus (HPV) vaccine provides strong, long-lasting protection against ...
2 Minute Medicine

FDA grants priority review for iberdomide-based myeloma regimen

The FDA has granted priority review for iberdomide, a first-in-class oral CELMoD designed to degrade transcription factors more effectively than earlier agents. 2. Priority review was supported by ...
2 Minute Medicine

Maternal exposure to environmental stressors is associated with decreased odds of infant survival among preterm infants

In this cohort of very preterm infants, maternal exposure to low levels of greenness, high levels of ozone, and low ...
2 Minute Medicine

Oral remibrutinib hits Phase 3 primary endpoint for inducible hives

Oral remibrutinib successfully met its primary endpoint in the Phase III RemIND trial, delivering significant symptom relief for chronic inducible urticaria. 2. As a selective BTK inhibitor, this ...
2 Minute Medicine

Higher sleep apnea-specific hypoxic burden may predict postoperative cardiovascular complications and mortality in obstructive sleep apnea

In this cohort of patients with Obstructive sleep apnea (OSA), a higher sleep apnea-specific hypoxic burden (SASHB) was associated with a significantly greater risk of 30-day postoperative ...
2 Minute Medicine

Merck and Mayo Clinic launch AI-driven precision medicine lab

Merck and Mayo Clinic have launched a strategic collaboration to integrate multimodal clinical data with AI to accelerate drug discovery and target identification. 2. The partnership leverages secure, ...
2 Minute Medicine

Lifestyle factors including higher body mass index and smoking are associated with changes in left-atrial size and function

In this prospective cohort study, lifestyle behaviours, especially higher body mass index (BMI) and smoking, are associated ...