Abstract:. Researchers utilized a two-vector system, consisting of an enveloped delivery vehicle and an adeno-associated virus to deliver CRISPR tools and a large DNA payload, to achieve stable and ...
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Major Finding: A novel approach to monitor bladder cancer via urine tumor DNA that overcomes the “field effect” was developed. Concept: The field effect, in which tumor-adjacent bladder acquires ...
*Corresponding Author: Sandra J. Casak, Office of Oncology Drugs, CDER, U.S. Food and Drug Administration, WO22 Room 2200, 10903 New Hampshire Avenue, Silver Spring ...
Although T cell–based therapies have shown great promise for treatment of hematologic malignancies, many barriers limit their success in solid tumor types. One such limitation is the scarcity of ...
To help defray the rising costs of initial manuscript screening and publication, the AACR journals levy fees as detailed herein. Authors are required to confirm at the time of submission that they ...
3State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, P.R. China. 2Department of Obstetrics and Gynecology, Development and Related ...