Lionel Messi's Inter Miami headline the quarter-final contenders, while Mexican powerhouse Tigres UANL and MLS outfit Seattle Sounders are also among the favourites.

The fact that Inter Miami has lifted both the Supporters’ Shield and the Leagues Cup since Messi’s arrival tells you almost everything you need to know about his impact. Before the Argentine joined, the club—founded in 2018—had never won a single piece of silverware.

After announcing the departure of Drake Callender, Lionel Messi could soon see his Inter Miami squad boosted by a young star from his boyhood club, Newell’s Old Boys.

Inter Miami will host the LA Galaxy at Chase Stadium on Saturday, August 16, 2025, at 7:30 p.m. ET/ 4:30 p.m. PT. Inter Miami is 6th in the Eastern Conference with a record of 12–5–6 (points 42) and Galaxy is at the bottom of the Western Conference with a record of 3–15–7 heading into the weekend.

Lionel Messi created history to script a new record in the match against the Los Angeles Galaxy that not even Cristiano Ronaldo could achieve.