POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

Prince Frederik, 22, was a founder and the creative director of a foundation that raised awareness of POLG disorder.

The prince had PolG disease, a genetic mitochondrial disorder that prevents the body's cells from producing adequate energy.

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Luxembourg's Royal Family has announced the death of Prince Frederick at 22 years old.

Prince Frederik of Luxembourg, who died at 22, spoke about the rare genetic disorder he navigated in a video released by The ...

Prince Frederik, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, died at age 22 on March 1 from ...

Prince Frederik, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, has died at the age of 22. He ...

Prince Frederik, the son of Europe's Prince Robert of Luxembourg, has died from a rare genetic disease, his family announced.

Prince Frederik of Luxembourg, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, has died after a ...

Frederik de Nassau died on March 1, in Paris, a day after internationally recognized Rare Disease Day, which takes place on ...