The type 1 IGF receptor (IGF-IR) is activated by two ligands, IGF-1 and IGF-2, and by insulin at supraphysiological concentrations. It plays a significant role in the growth of normal and abnormal ...

Researchers studying over 2,000 Ashkenazi Jewish centenarians uncovered two rare IGF-1 gene variants linked to exceptional ...

a recombinant anti-insulin-like growth factor 1 receptor (IGF-1R) antibody) for the treatment of thyroid eye disease (TED). As China's first and the world's second approved IGF-1R antibody drug, ...

Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to advance his research on viral insulins into the understanding ...

The treatment was approved by China’s National Medical Products Administration (NMPA) and is China's first, and the world’s ...

The disease is characterized by a mutation in the growth hormone receptor gene that causes short ... people affected by Laron ...

People with a rare genetic mutation that causes short stature and may also make them live longer are helping shed light on the causes of ageing. Those with the unusual gene variant have several ...

Figure 1: Reduction in IGF-I receptor mRNA in HaCaT cells following treatment with antisense oligonucleotides. We investigated the sequence dependence of the inhibitory effect of one of the ...

a recombinant anti-insulin-like growth factor 1 receptor (IGF-1R) antibody) for the treatment of thyroid eye disease (TED). As China's first and the world's second approved IGF-1R antibody drug ...

("Innovent") (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high-quality medicines for the treatment of oncologic, autoimmune, cardiovascular and ...