This script maps residue numbering and chains between a UniProt ID and a PDB structure. It can also find all structures or the best structure for a protein. I wrote this because I was fed up with the ...

The energetic fitness of histidine in each of its three protonation states has been investigated for NMR-determined protein structures by using molecular mechanics calculations. The protein structures ...

The HER2 extracellular domain (ECD) can be released by proteolytic cleavage by tissue metalloproteinases [31] and thereby shed into the circulation. Negative 0/1+ None, or weak incomplete membrane ...

Genetic information in eukaryotic cells is stored in chromatin, which packs DNA and histone proteins in an organized and compact structure. (1) The basic unit of chromatin, the nucleosome, is usually ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

Herceptin SC contains the active ingredient trastuzumab. Herceptin SC is used to treat breast cancer whose tumour has tested positive to HER2. For more information, see Section 1.