For decades, lab-made antibodies have been used to support patients fighting specific diseases. These treatments have become ...

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

The truncated form of HER2 (p95HER2) that lacks trastuzumab-binding domain can no longer be inhibited by trastuzumab. The remaining structure can still dimerize ... antibody-dependent cellular ...

UNIGE scientists have developed a groundbreaking technology that creates synthetic molecules mimicking antibodies, potentially revolutionizing disease treatments.

CAR structures of CAR-Ms. The CAR structure in CAR-Ms shares similarities with that ... it was demonstrated that these modified cells could recognize and attack beads coated with proteins found on ...

The following highlights showcase the most pivotal, innovative research published across multiple therapeutic areas in ...

HER2-positive (HER2+) breast cancer treatments come with a range of unpleasant side effects. However, there are strategies ...

Eating well can help support your immune system and maintain strength and energy if you have HER2-negative breast cancer, ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...