Joseph Mossel is the CEO of Ibex Medical Analytics. His career in the tech industry spans more than 20 years, starting off in ...

The company said that patients with advanced HR+/HER2- breast cancer and TNBC still ... is an enzyme that is involved in cell division and proliferation, and is often overexpressed in cancers.

Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering ... of sorafenib in patients with HER-2 negative locally advanced or MBC: Trial 1: the ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

Seagen is a specialist in antibody-drug conjugates, but has looked to Chinese biotech RemeGen for a HER2-targeting candidate that could challenge rival drugs from AstraZeneca/Daiichi Sankyo and Roche.

REVEAL GENOMICS ®, a pioneering Barcelona-based biotech company dedicated to advancing precision oncology, is proud to announce the publication of a groundbreaking study demonstrating the clinical ...

Breakthrough Cardiac Regeneration Research Offers Hope for the Treatment of Ischemic Heart Failure Mar. 7, 2025 — The discovery of a novel approach to promote cardiomyocyte proliferation offers ...

The role of cancer associated fibroblasts (CAF) in immunotherapy response of gastric cancer (GC) is elusive. Here, by single cell sequencing, spatial transcriptomic and functional evaluation, the ...

Second, since EOGC is a highly heterogeneous disease with multiple molecular subtypes, we only focus on the biomarker differences among Lauren’s type, HER-2 status and PD-L1 status, which should be ...

Objective To monitor trastuzumab resistance and determine the underlying mechanisms for the limited response rate and rapid emergence of resistance of HER2+ metastatic gastric cancer (mGC). Design ...

Naughty Dog and Sony revealed The Last of Us Part 2 Remastered for PC with a new trailer during The Game Awards, but there's not much to glean in terms of differences for the PC release. It's all ...