National MS Education and Awareness Month is celebrated each year in the US in March, after having been launched in 2003 by ...

Ponatinib, a multi-targeted tyrosine kinase inhibitor originally used to treat leukemia ... The PCR-amplified products were electrophoretically separated on 3% agarose gel in Tris–acetate–EDTA (TAE) ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Lupron is the brand name for leuprolide acetate. It belongs to a class of drugs called luteinizing hormone-releasing hormone (LHRH) agonists. These medications block the production of LHRH in the ...

Proper activation of STING signaling requires STING translocation and phosphorylation. Here, we show that dual serine/threonine and tyrosine protein kinase (DSTYK) directly phosphorylates STING Ser366 ...

Your body produces the enzyme creatine kinase (CK) or creatine phosphokinase to keep your muscles functioning properly. Healthcare providers use the CK test to check levels of this protein in your ...

Production of methane by methanogenic archaea, or methanogens, in the rumen of ruminants is a thermodynamic necessity for microbial conversion of feed to volatile fatty acids, which are essential ...

Notch1 is expressed uniformly throughout the mouse endocardium during the initial stages of heart valve formation, yet it remains unclear how Notch signaling is activated specifically in the AVC ...

Hepatocellular carcinoma (HCC) poses a serious threat to human health. Identifying diagnostic and therapeutic targets from plasma proteins is essential for early HCC detection and treatment.