Pakistan ordered businesses, schools and public offices in Karachi to shut on Wednesday after torrential monsoon rain left at least 10 people dead in the densely populated port city, with more heavy downpours predicted.

At least 21 people have died in monsoon rain-related incidents in Pakistan, authorities said, pushing the nationwide death toll over the last week above 400 as floods and landslides continue to devastate large parts of the country.

A deluge of rain triggered floods and landslides, sweeping people away and flooding and destroying homes, officials said.