Researchers describe new molecular mechanisms linked to insulin resistance
The results also reveal how protein levels of ephrin receptor tyrosine kinase B4 (EphB4)—a factor that binds to InsRβ and ...
Nature4y
Asymmetric dimerization of EGFR kinase domains
The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?
Nature2y
Blocking BTK in B-cell disorders
Now, Honigberg and colleagues describe an orally available, potent and selective inhibitor of the B-cell receptor (BCR) signalling molecule Bruton's tyrosine kinase (BTK), which shows promising ...