When neuroscientists analyzed the exact properties of nerve connections in the brain, they made a startling observation: At a key connection, or synapse, messages are sent against the usual stream of ...

Tau proteins are involved in more than twenty neurodegenerative diseases, including various forms of dementia. These proteins clump together in patients’ brains to form neuronal tangles: protein ...

This tidy volume recounts an exciting and important piece of neuroscience history, when investigators strove to understand the basis of synaptic transmission. The recognition of Cajal's 'neuron ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

BIRMINGHAM, Ala. – Transduction is the changing of one form of energy into another, such as a spoken voice changed into radio waves by a cellphone. Ten years ago, three research teams published a ...

One of the greatest, relatively underappreciated, discoveries in all of science was the discovery of the nerve impulse in the 1930s by the British Lord Adrian. Adrian did win a Nobel Prize for his ...

While the role of barrier function in establishing a protective, nutrient-rich, and ionically balanced environment for neurons has been appreciated for some time, little is known about how signaling ...

BIN1, one of the strongest genetic risk factors for late-onset Alzheimer’s disease, encodes a protein that dabbles in many cellular functions, taking a hand in Aβ production, tau propagation, and ...

Controversy is an inevitable, and essential, part of science, but one that scientists generally find uncomfortable and tend to regard as a blemish to be hidden from the public. Elliot Valenstein's ...

Also referred to as chemical messengers, neurotransmitters are chemical agents made and released by neurons. They are stored in vesicles at the terminal end (presynaptic terminal) of a neuron. Their ...

Ten years ago, three research teams published a breakthrough — the first description of the molecular mechanism for transduction in fingertip sensory Merkel cells that can transduce gentle touch, a ...

One of the greatest, relatively underappreciated, discoveries in all of science was the discovery of the nerve impulse in the 1930s by the British Lord Adrian. Adrian did win a Nobel Prize for his ...