Why then would most of the crystallized forms of EGFR show the receptor in its active conformation? Most likely, the crystallization process necessary for analyzing protein structure caused a high ...

In collaboration with Professor Young-Tae Chang's team, they identified its structure ... and protein interactions. Their findings revealed that epidermal growth factor receptor (EGFR)—a key ...

In collaboration with Professor Young-Tae Chang's team, they identified its structure ... and protein interactions. Their ...

Because it only takes nanoseconds to microseconds for a protein to morph along its path to its final structure, the scientists needed to slow down the process during their analysis to be able to catch ...

Researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences and the Shanghai Institute of Organic Chemistry have divulged EGFR (L858R/T790M/C797S triple mutant) and ...

Learn about our Editorial Policies. While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and ...

EGFR is short for epidermal growth factor receptor. It’s a protein that helps cells grow, and it’s found in both healthy cells and cancer cells. A mutation in this gene can cause cells to ...