The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a ... of Syk tyrosine kinase binding to membrane immune receptors and ...

Blood cancer patients who receive a type of anti-cancer therapy should continue to take the drug while having COVID-19 ...

ERBB receptors are regulated by their own intrinsic properties as well as by external associated proteins. What is regulation, where does it occur on the receptor, and how do scientists study it?

RET, a transmembrane receptor tyrosine kinase ... with less potency against other protein tyrosine kinases. The drugs have shown similar potency against both wild-type and gatekeeper mutated ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.