The researchers captured eight unique structural models and 16 cryogenic electron microscopy maps of the receptor with both ...

NEW YORK (Reuters Health) - Activation of delta opioid receptors inside cells is important for the relief of inflammatory pain, researchers report. "Most medicines targeting receptors are designed to ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...

Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed a novel molecule that binds to and blocks a previously unrecognized opioid receptor ...

The body's endogenous opioid system has three classes of opioid receptors: mu, delta, and kappa. Previous research showed that mice lacking the mu opioid receptor do not drink alcohol. A new study ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

To date, therapies for multiple sclerosis (MS) focus on modifying or suppressing the immune system rather than on remyelination. Recent findings have pointed to the κ-opioid receptor (KOR) as a ...