It's true the Titans secondary is occupied by practice squad players, but 13.5 points is a lot. I'm not calling for an upset, but don't forget that this Jaguars team has lost to the Titans in a critical Week 18 spot before.

Cowboys (-3.5) at Giants: The Raiders understood the assignment in their Week 17 Tank Bowl loss against the Giants. This dumbass Giants team did not. The Giants are going to try to win this game too, but so will Dak Prescott, who has a chance to lead the NFL in passing yards.

Chris Vasile breaks down his favorite NFL picks against the spread for Week 18, including the Carolina Panthers and Baltimore Ravens.

Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

We're down to the final week of the 2025 regular season. Playoff teams are figuring out whether to play their starters or go with backups to avoid key injuries. So, what's the motivation for clubs eliminated from postseason contention?

Two win-or-go-home games. Two games to decide the AFC South champs. And a Seahawks-49ers game will determine the NFC's top seed. Nice.

Although the Arizona Cardinals have lost five games in a row, you can't blame that skid on quarterback Jacoby Brissett, who has balled out since replacing the injured Kyler Murray. My NFL picks have been riding the hot hand with Brissett the last few weeks ...

Picking the Ravens over the Steelers is almost too easy. We also like the Seahawks over the 49ers and Bucs over Panthers in critical games.

Look for the Raiders to win the No. 1 overall pick by losing to the Giants, and for the Bucs and Panthers to set the stage for a Week 18 showdown to decide the NFC South.

The Broncos are 14-point favorites in the latest Chargers vs. Broncos odds at DraftKings, and the over/under for total points scored is 37.5. Denver's over/under for total points scored is 26.5, while Los Angeles' is 10.