New research in an animal model of aging suggests a possible mechanism for why people with early menopause or other genetic conditions affecting the reproductive system are more likely to get ...

In the choreography of meiosis—the process responsible for sex cell division in all eukaryotic life—the pairing of homologous chromosomes (homologs) is essential. Errors in this process can lead to an ...

Chromosomes carry genetic information. Meiosis is a cell division process that produces germ cells - sperm and egg in animals, pollen and egg in plants - with half the usual chromosome number. During ...

Purpose: We evaluated whether the association of socioeconomic risk factors for trisomy 21 differed by type of maternal meiotic error. Methods: We determined meiotic ...

Chromosome aneuploidy is a major cause of pregnancy loss, abnormal pregnancy and live births following both natural conception and in vitro fertilisation (IVF) and increases exponentially with ...

As viewed from a human perspective, nature has done some ingenious engineering to overcome some of the obstacles it has faced. Take the evolution of sex, for instance. To make the move from asexual to ...

More than one-sixth of adults around the world experience infertility in their lifetime. There is a high unmet need not only for increased access to affordable, high-quality fertility care for those ...