Antibody-drug conjugates have had a tremendous impact on breast cancer care and treatment, according to Dr. Charles E. Geyer.

The collection of proteins within a cell determines its health and function. Proteins are responsible for nearly every task of cellular life, including cell shape and inner organization ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

"CAR-T cells can function as a platform where ... Initially, the trial will recruit patients with HER2-driven tumors ...

MED1 plays key roles in mediating treatment resistance with estrogen receptors (ERs) and the protein HER2, but researchers ..

SPEAKER: [MUSIC PLAYING] [TYPING] If you have breast cancer, your doctor will need to look at a number of different things before coming up with a treatment plan. This will include how far the ...

Trastuzumab works by binding to HER2 proteins that are found on the cells of HER2-positive breast cancer. By binding to those proteins, it helps deliver the chemotherapy drug to the targeted tumor ...

Eukaryotes use different families of chaperone proteins, although they function in similar ways. Chaperone proteins are abundant in cells. These chaperones use energy from ATP to bind and release ...

Triple-positive breast cancer is a type of breast cancer that tests positive for estrogen receptors, progesterone receptors, and high levels of HER2 protein. Some types of breast cancer cells use ...

The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many other molecules and structures inside organisms. The shape of a ...