This vampire isn't interested in the blood that runs through your veins, though. The white dwarf in question, designated Gaia22ayj and located around 8,150 light-years from Earth, is ravenously ...

More information: FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development, Cancer Research (2025). DOI: 10.1158/0008-5472.CAN-24-4576 ...

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2 ...

When they targeted FGFR2 along with EGFR-a protein known to be overactive in pancreatic cancer-they saw even better results. Fewer "early versions of cancer" formed in the first place.

Notably, FGFR2 expression in murine precancerous lesions correlated with an increase in mutant KRAS signaling. "We know that precancerous pancreatic lesions often carry KRAS mutations," said Tonelli.

Aberrations in fibroblast growth factor receptors FGFR2/3 are major drivers of many cancers—including intrahepatic cholangiocarcinoma, endometrial, breast, gastric, and bladder cancers. However ...

“These data provide important early evidence that RLY-4008, or lirafugratinib, has the potential to help both patients with FGFR2-fusion cholangiocarcinoma as previously reported, as well as ...