An international team of experts in embryology and bioethics has published the first white paper on the use of embryonic ...

Caltech researchers have developed a powerful new method for creating embryo-like structures from stem cells that could transform how we study fertility. Using stem cells rather than a traditional ...

In human embryos, major zygotic genome activation (ZGA) initiates at the 8-cell (8C) blastomere stage, marking the start of the ontogenesis program. Recent advancements have shown that primed human ...

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic ...

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), ...

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...

For the first time, stem cells typically considered restricted to forming body tissues spontaneously formed a yolk-sac-like structure in a model of the human embryo. Stem cell models of human embryos ...

The mechanistic role of trisomy 8 in the development of myelodysplastic syndrome (MDS) remains poorly defined. Here, we generated a trisomy 8 mouse model by transferring a human chromosome 8 into ...

Researchers led by developmental biologist Kathy Niakan at the University of Cambridge have used base editing in human embryos to learn more about human embryonic development. By deactivating a gene ...